there are a few 3d sculpting modules out there . i've seen atleast one going around where you use a pen that can be tracked in 3d dimensions. i was actually sugesting that this should be used for 3d modeling it wouldnt make that much of difference since mice offer 2d input aswell . it would just be a less stress full way of working with programs

. since it detects multiple inputs you could move objects with both hands or tie actions (shortcuts,hotkeys etc.) to different fingers.